nef protein การใช้

• This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1.
• The other end of the nef protein carries an address label, readable by the cell's internal sorting system that directs proteins to their proper place.
• The study involved giving participants three vaccinations of gag, pol, and nef proteins from HIV . The replication-deficient adenovirus vector carried these HIV-1 genes into the cell.
• The message carried by the nef protein attached to the base of the flagpoles says, in the cell's sorting code, " Haul to garbage dump and recycle, " tricking the infected cell into pulling down its flagpole proteins and destroying them.